Hereditary Angioedema: The First Case Reports from Afghanistan

jawad mohammad Jawad; Ali Nawrozie; Gul Zanin Sohaili; Mohammad Reza Shojaie; Nooria Mohammady; Khatera Naimi

doi:10.62134/ajbms/v2.i2.khatamuni.11

Authors

jawad mohammad Jawad Department of Internal Medicine, Khatam Al-Nabieen University, Kabul, Afghanistan
Ali Nawrozie Department Of Cardiology, Hemat Specialized Health Complex, , Kabul, Afghanistan.
Gul Zanin Sohaili Department Of Cardiology, French Medical Institute for Mothers and Children, Kabul, Afghanistan.
Mohammad Reza Shojaie Internal Medicine Specialist, Barchi 50 Beds Hospital, Kabul, Afghanistan.
Nooria Mohammady Kabul University of Medical Sciences, Kabul, Afghanistan.
Khatera Naimi Department of Midwifery, Khatam Al-Nabieen University, Kabul, Afghanistan

DOI:

https://doi.org/10.62134/ajbms/v2.i2.khatamuni.11

Abstract

Background: Hereditary angioedema is an uncommon condition characterized by a wide range of symptoms, including edema of the skin, gastrointestinal mucosa, and larynx or throat. Even though there are three varieties, the most common is type I, which is caused by a lack of the complement C1 inhibitor.

Case presentation: Herein, we describe the cases of Afghan patients diagnosed with HAE. The patients presented shortness of breath, swelling, and swelling in the face, hands, and feet. In all three cases, symptoms such as numbness in the face, hands, and feet, hoarseness, and alterations in the normal form of the face are observed.

Conclusion: HAE diagnosis is frequently a complex and time-consuming process. It necessitates a thorough physical examination, with a focus on the circumstances and frequency of clinical symptoms, as well as an in-depth review of the family history. Understanding the physical examination and the analysis of specified laboratory testing is critical to arriving at an accurate diagnosis.